PMR

Polymyalgia rheumatica (PMR) is an inflammatory disorder characterized by muscle pain and stiffness, particularly in the shoulders and hips. It primarily affects older adults, usually those over 50, with a higher incidence in women and individuals of Northern European descent. The cause of PMR is not well understood, but it is thought to be an autoimmune condition where the body's immune system mistakenly attacks healthy tissues. Symptoms often appear suddenly, typically manifesting as aching and stiffness in the morning or after periods of inactivity, fatigue, a general feeling of illness, and sometimes low-grade fever.

Diagnosing PMR can be challenging as symptoms may resemble those of other conditions such as rheumatoid arthritis or fibromyalgia. There is no specific test for PMR, so diagnosis is primarily based on clinical presentation and elevated inflammatory markers in the blood, such as the erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). Treatment generally involves low doses of corticosteroids, which can quickly relieve symptoms. The duration of treatment varies, but most patients require therapy for at least one to two years. Regular monitoring and follow-up care are essential due to the potential side effects of long-term corticosteroid use and the association of PMR with an increased risk of developing giant cell arteritis, a related condition that can cause vision loss if untreated.