Crohns
Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract, characterized by segmental and transmural inflammation that can affect any part of the digestive system, from the mouth to the anus. The inflammation often leads to deep ulcers and may cause a range of symptoms including abdominal pain, diarrhea (which may be bloody), weight loss, fatigue, and malnutrition. Crohn's is considered an autoimmune disease, where the immune system mistakenly attacks the body's own tissues, though the exact cause is not fully understood. Genetic predisposition, environmental factors, and an abnormal reaction to gut bacteria may play roles in the disease's development.
Diagnosing Crohn's disease involves various tests, including blood tests, stool studies, endoscopic procedures, and imaging studies. Treatment is aimed at reducing inflammation, managing symptoms, and maintaining remission. This can include the use of anti-inflammatory drugs, immune system suppressors, antibiotics, or biologic therapies that target specific processes in the immune response. Surgery may be necessary for those who do not respond to medication or develop complications. While there is currently no cure for Crohn's, with appropriate medical management, many individuals with the condition lead active and fulfilling lives.