Crohn's Disease and Its 10 Symptoms

Crohn's disease is an inflammatory bowel disease that causes inflammation in the digestive tract, affecting areas from the mouth to the anus. Symptoms typically occur in the small intestine and colon. While the exact cause is unknown, heredity and immune system issues may contribute. Risk factors include being under 30, urban living, smoking, certain medications, and ethnic background.

Frequent Diarrhea

A common symptom of Crohn's disease is frequent diarrhea, caused by inflammation that disrupts water and electrolyte absorption. This leads to stools retaining excess fluid. In Crohn's, diarrhea may also result from increased bile acids. Bloody diarrhea occurs when the gastrointestinal lining is damaged, allowing blood and serum to leak into the stool.

Ulcer Development

People with Crohn's disease often develop ulcers in the mouth, stomach, and intestines. Mouth ulcers, which are small and painful, typically form along the gums, making chewing and swallowing difficult. Causes include vitamin deficiencies, medication side effects, and inflammation. Peptic ulcers occur when stomach acid damages the protective lining of the stomach and gastrointestinal tract.

Nausea and Persistent Vomiting

As Crohn's disease progresses, symptoms often worsen. Initially, nausea and vomiting may occur occasionally, but they become more frequent over time. This can be due to inflammation irritating the stomach or causing scarring in the small intestine, which obstructs the digestive tract and triggers these symptoms.

Constipation and Bowel Obstructions

Throughout Crohn's disease, some individuals may experience constipation. Initially, this can be due to inflammation. Bowel obstructions, a common complication, often cause constipation and can also lead to vomiting. The severity of symptoms depends on the size and degree of the blockage.

Weight Loss

Weight loss is common in Crohn's disease due to several factors. Frequent vomiting and diarrhea contribute to this, as do nutrient deficiencies and malabsorption. Additionally, symptoms like mouth ulcers and stomach pain may cause individuals to avoid eating, further leading to weight loss.

Anemia

Many people with inflammatory bowel disease develop anemia, though it is often overlooked by doctors. This is usually due to iron deficiency from chronic blood loss in the gastrointestinal tract. Inflammation also hinders iron absorption from food and supplements. Unabsorbed iron can sometimes become toxic, worsening Crohn's disease symptoms.

Fever

A fever can be a symptom of progressing Crohn's disease, though it is uncommon early on. Fevers are thought to be part of the inflammatory process but can also result from certain medications. For some, a fever signals potential complications. Abscesses, or pus collections, can cause fevers, as can a toxic megacolon—a severe complication where the large intestine dilates, worsening Crohn's symptoms.

Fatigue

Many studies show that most people with Crohn's disease experience fatigue, regardless of the disease's progression. Pain and discomfort often disrupt sleep, while anemia also contributes to fatigue. Additionally, managing Crohn's, undergoing treatment, and dealing with symptoms can lead to anxiety or depression, further exacerbating fatigue.

Sores or Eye Swelling

Some people with Crohn's disease experience extraintestinal symptoms, affecting areas beyond the gastrointestinal tract. About 10% develop eye irritation or inflammation, leading to blurred vision, eye pain, and light sensitivity. In severe cases, chronic inflammation can cause permanent damage and vision loss. While these issues are typically due to the disease's inflammation, they can also result from treatments like corticosteroids.

Arthritis

Another common extraintestinal symptom of Crohn's disease is arthritis, affecting nearly 30% of individuals with the condition. Although linking arthritis directly to inflammatory bowel diseases can be challenging, it is generally less severe than other forms of arthritis due to its association with gastrointestinal inflammation. The joints typically do not experience significant damage, and symptoms often improve with treatment of the underlying disease.

Foods That May Help Manage Crohn's Disease

Crohn’s disease, a type of inflammatory bowel disease (IBD), affects three million Americans annually. People with Crohn’s may restrict their diet to alleviate symptoms, but this can lead to malnutrition, decreased bone strength, and growth delays. However, diet plays a crucial role in managing the condition. By selecting appropriate foods, individuals with Crohn’s can enjoy a varied diet, manage symptoms, and reduce the risk of malnutrition. It's important to consult a doctor for personalized dietary advice.

Low-Fiber Carbohydrates

Fiber is an important topic in the context of IBD, with many studies exploring the appropriate amount and type for those affected. People with Crohn's should include fiber in their diet but may benefit from a low-fiber diet during flare-ups, as high-fiber foods can exacerbate symptoms. Those with a narrowed bowel or obstruction are often advised to follow a low-fiber diet. Low-fiber carbohydrates include white rice, bread, and pasta.

Low-Fiber Fruit and Vegetables

To maintain a balanced diet, it's important to include fruits and vegetables, even on a low-fiber diet. During a flare-up, opt for well-cooked vegetables without skins, seeds, or stems, and avoid raw or steamed vegetables, beans, and cruciferous types like cabbage and cauliflower. Low-fiber fruit options include cooked or canned fruits, juices, and small amounts of honeydew melon and ripe banana. Avoid raw and dried fruits, especially prunes.

Lean Protein

Protein is essential for healing and muscle building, and people with Crohn's disease often need more due to bowel inflammation. However, high-protein foods can also be high in fat, which may worsen symptoms. Good sources of lean protein include fish, poultry (skinless white meat), soy, and eggs.

Oily Fish or Fish Oil Supplements

Fatty acids help reduce inflammation, and omega-3s may be beneficial in preventing and treating Crohn's disease. Research indicates they can decrease disease activity and improve quality of life. Omega-3s are primarily found in oily fish and are available as supplements.

Fermented Foods

Probiotics, found in certain foods and supplements, boost beneficial gut bacteria. While specific research on Crohn's is limited, evidence supports their benefits for other IBD conditions. A study showed probiotics can stabilize the intestinal barrier and reduce symptoms in children. Good sources include fermented foods like live yogurt, kombucha, and kimchi, as well as supplements.

Foods Containing Vitamin D

Vitamin D aids in calcium absorption for healthy bones and may help fight infection and reduce inflammation. Limited research suggests it could benefit Crohn's management. Our bodies produce vitamin D from sunlight, and it can also be obtained from foods like fortified plant-based milks, salmon, tuna, and sardines.

Turmeric

Research indicates that curcumin, a natural compound in turmeric, may aid in treating ulcerative colitis due to its anti-inflammatory properties. It could also be beneficial for Crohn's disease. Turmeric can be easily incorporated into recipes or taken as a supplement.

Low-FODMAP Foods

A low-FODMAP diet may help manage symptoms during a Crohn's flare-up. FODMAPs are gas-producing carbohydrates that can be difficult to digest, such as fructose, lactose, and gluten. Low-FODMAP foods include dairy-free milk, eggs, meat, oats, and rice. This diet is very restrictive and should be followed under the guidance of a healthcare professional.

Fluids

During Crohn's flare-ups, dehydration can occur from fluid loss due to diarrhea or reduced intake due to nausea. Mild dehydration may cause dry mouth, headaches, fatigue, and low energy, while chronic dehydration can lead to kidney issues. To stay hydrated, drink plenty of water and herbal tea, but avoid sugary drinks, caffeine, and alcohol, as they can worsen symptoms.

14 Early Signs of Schizophrenia

Schizophrenia is a multifaceted psychiatric disorder that impacts an individual’s cognitive functions, emotions, behaviors, and interpersonal relations. Its etiology is multifactorial, with potential contributors including genetic predisposition, environmental factors, neurochemical imbalances, psychological stressors, and prior use of psychoactive substances. The onset of symptoms typically occurs in late adolescence to early adulthood, between ages 16 and 30. While there are currently no definitive laboratory diagnostics for schizophrenia, medical professionals conduct thorough assessments based on symptomatic manifestations which are grouped into positive, negative, and cognitive categories. The diagnosis necessitates careful consideration, particularly given the condition’s tendencies to exhibit fluctuating periods of exacerbation and remission.

Delusions

Approximately 90% of individuals with schizophrenia exhibit delusions, which are irrational and unfounded beliefs considered as one of the positive symptoms critical in diagnosing the condition. It is important to clarify that the term "positive symptoms" refers to the presence of distorted thought or sensory processes, not beneficial aspects of the disorder. For example, patients may harbor unfounded fears about others reading their thoughts or believe they are the target of surveillance. Some patients may misinterpret media content or public figures as concealing personal messages directed at them. Others might feel they are subject to conspiracies or at risk of being poisoned. Delusions of grandeur are also common, with some patients convinced that they possess extraordinary abilities or embody notable historical or religious personalities. These delusions persist despite evidence to the contrary.

Hallucinations

Hallucinations are recognized as a prominent feature of schizophrenia, with roughly 70% of those diagnosed experiencing these phenomena. These hallucinations can manifest in various forms—auditory being the most frequent, followed by visual and olfactory. Auditory hallucinations typically involve hearing voices that may be perceived as menacing or whispering, whereas visual ones include seeing non-existent entities or lights. Olfactory hallucinations encompass distorted taste or smell sensations, which may lead to adverse effects such as an aversion to eating due to the perception that food is contaminated. It is important to differentiate these hallucinations—sensory experiences without external stimuli—from delusions, which are firmly held false beliefs. Both symptoms can be distressing for the individual and are treated as a serious aspect of the condition by healthcare professionals.

Bizarre or Disorganized Behavior

Schizophrenia is characterized not only by its positive symptoms but also by disorganized and at times bizarre behaviors that clinicians consider when making a diagnosis. Although these actions may appear non-goal-oriented to an observer, they hold significance for the affected individual. Such behaviors can manifest as diminished inhibitory control and impulsive actions that may be irrational or inappropriate in given contexts. Consequently, this can interfere with the individual's ability to perform tasks essential for daily living and self-care.

Speech Abnormalities

Emerging studies suggest that disorganized speech may be a key characteristic of schizophrenia, challenging the traditional notion that the disorder springs primarily from impaired thought processing. Experts assert that abnormalities in speech can reflect fundamental symptoms of schizophrenia. Individuals with this disorder manifest atypical language patterns, distinguishing them from those without the condition. They may struggle to remain on topic during a conversation or construct logically coherent sentences. Additionally, schizophrenia may disrupt the attribution of personal agency in self-referential thoughts, leading to atypical expressions – for example, using "he" instead of "I" when referring to oneself. These linguistic deviations provide insight into the cognitive disruptions associated with schizophrenia.

Disorganized Speech

Individuals with schizophrenia may exhibit challenges with concentration and sustaining coherent thoughts. Disorganized speech, a notable symptom, involves answering questions in a disjointed or logically inconsistent manner, or rapidly jumping between unrelated subjects. Additionally, some may create words or phrases unique to them, which can appear incoherent or nonsensical to listeners. A specific speech pattern known as clang involves the utterance of rhyming words that may lack discernible meaning, as the association of words is based on sound rather than on logical concepts.

Psychomotor Problems

Increased motor activity, characterized by repetitive behaviors or uncommon gestures, is a distinctive positive symptom of schizophrenia. Individuals with this condition may exhibit signs of impaired coordination and motor skills. Furthermore, schizophrenia can affect sensory integration—the cognitive capacity to synthesis and respond to various sensory inputs, including tactile, vestibular, proprioceptive, visual, auditory, olfactory, gustatory, and gravitational information. Additionally, psychomotor symptoms could include increased muscular tension and the occurrence of tremors even when the body is at rest. These psychomotor abnormalities are significant indicators of schizophrenia and are critical for diagnosis and treatment planning.

Altered Sleep Patterns

Individuals with schizophrenia frequently suffer from related sleep disorders, often signaling the disease's emergence. Experts in mental health recognize that those affected generally endure a combination of sleep-related issues, such as insomnia, sleep apnea, and restless leg syndrome. Additionally, some may experience periodic limb movement disorder, characterized by involuntary limb movements during sleep, which differs from restless leg syndrome as it doesn't disrupt sleep directly. These sleep disturbances can aggravate schizophrenia symptoms, potentially leading to severe psychotic episodes.

Cognitive Impairments

Schizophrenia is acknowledged by mental health professionals as a condition that primarily affects cognitive functions, considered a fundamental aspect of the disorder. Individuals diagnosed with schizophrenia may experience significant challenges in performing tasks reliant on working memory, such as retaining a telephone number, devising strategies for problem-solving, or organizing activities. Furthermore, their ability to form and maintain long-term memories is often impaired, making the assimilation of new information arduous. The illness also has the propensity to diminish mental agility and response times, which can have a profound impact on someone's abilities in sports and creative endeavors.

Negative Symptoms

Individuals in good mental health typically demonstrate a range of normal behavioral patterns. Mental health professionals identify the lack of these behaviors as negative symptoms, which are key indicators in diagnosing schizophrenia. Assessing these negative symptoms can be challenging for clinicians, as they are often similar to those observed in clinical depression. Patients with schizophrenia may exhibit a diminished emotional response, reduced eye contact, and muted facial expressions. Other indicative behaviors include social withdrawal, a lack of motivation, and a diminished capacity to experience pleasure or joy. It is important to note that negative symptoms of schizophrenia may fluctuate or worsen over time.

Early Warning Signs

Schizophrenia often presents with a progressive onset rather than abrupt symptoms. Individuals may exhibit a noticeable change in behavior as observed by those close to them, including a lack of motivation, reduced emotional response, and indifference towards their environment. Attention span may decline, leading to impaired performance at work or school. A person with schizophrenia might also show a lack of concern for personal appearance, withdraw from previously enjoyed activities, and become more isolated. Additionally, they may express unconventional thoughts or exhibit signs of suspicion. This complex condition necessitates a nuanced and compassionate understanding.

Affective flattening

Affective flattening is a significant but frequently underestimated symptom of schizophrenia. Characterized by a severe reduction in the expression of emotions, individuals with this condition may exhibit a blank facial expression, monotone speech, and reduced eye contact. These symptoms can impede their ability to forge connections with others, often resulting in increased isolation from their social and support networks.

Avolition

Avolition is a symptom in schizophrenia marked by a profound deficit in motivation, influencing an individual's ability to begin and pursue various tasks. This condition can result in substantial disruption to daily life, as affected individuals might find it challenging to engage in fundamental self-care routines, including maintaining personal hygiene, or participating in occupational, educational, or social endeavors. The lack of activity can intensify the tendencies toward social withdrawal and isolation that are frequently associated with schizophrenia.

Alogia

Alogia, characterized by a reduced capacity to express thoughts verbally, is a recognized cognitive symptom of schizophrenia that adversely affects communication. Affected individuals may provide limited and unelaborated responses or might demonstrate reluctance in initiating conversations. Often, their speech lacks substance, or they resort to terse, monosyllabic replies. These communication difficulties can hinder effective conversation, exacerbate social isolation, and pose challenges in understanding the individual's thoughts and needs.

Anhedonia

Anhedonia describes a reduced capacity to feel pleasure or maintain interest in once-enjoyable activities, representing a significant symptom for those with schizophrenia. It frequently manifests as a dwindling enthusiasm for hobbies, social engagements, and personal relationships, often leading to a self-perpetuating loop of retreat and seclusion. Addressing anhedonia is vital to enhancing life quality for individuals with schizophrenia, and thus, demands careful consideration and intervention in their ongoing care.